When the dull but clever Howard Marks goes to Oxford University he is introduced to different types of drugs. Soon he becomes a reseller and then a spider in an elaborate trafficking business.
As his empire grows, problems arise, but usually Marks overcomes them with his amusing Welch way of handling things. Getting caught up in Irish independence conflicts, Middle Eastern conflicts he ends up trying to penetrate the biggest market in the world: America.
Naivity, humor and practicality bring Marks a long way, but eventually he is stopped in his endeavors and he finds another, legal, way to use his fame.
“Mr. Nice” is an amusing film about the 1970’ies and 1980’ies drug scene.